CD19 anticorps (PE)

N° du produit ABIN6655430

N° du produit (Fournisseur): 200-308-n24

Cet anticorps anti-CD19 est un anticorps Souris Monoclonal détectant CD19 dans FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CD19 anticorps (PE) (ABIN6655430)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: HIB19

Détail du produit anti-CD19 anticorps (PE)

N° du produit (Fournisseur): 200-308-n24

Fournisseur: Rockland

Fonction: CD19 Phycoerythrin Antibody

Réactivité croisée (Details): Reactivity is observed against human CD19 and chimpanzee.

Purification: Phycoerythrin conjugated CD19 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD19.

Stérilité: Sterile filtered

Immunogène: Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with CD19 antigen.

Isotype: IgG1 kappa

Labeling Ratio: 1-2

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 5 µL/1x10e6 cells or 100μL of whole blood

Commentaires:

Anti-CD19 is tested for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Références pour anticorps anti-CD19 (PE) (ABIN6655430)

Bradbury, Goldmacher, Tedder: "The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 6, pp. 2915-27, (1993) (PubMed).

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet:

Synonyms: B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19

Background: CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

Gene Name: CD19

ID gène: 930

NCBI Accession: NP_001171569

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway